Big move coming

I have posted previously (several times, in fact) re the growing opportunity for us investors in Isis Pharmaceuticals/ISIS. Remember, among its other pipeline opportunities, this company has a key statin deep into the clinical trials process, and all accounts have it that this drug shows a marked improvement over other statins currently available or in trials. (Including the one from Arena Pharmaceuticals/ARNA.) This helps make the company a leading takeover candidate by an old-line ethical drug manufacturer such as Pfizer/PFE, whose own drug felled its hopes to create one internally. (Verily, half of that drug was the result of the wholesale purchase of another company to obtain its drug!) I prefer a buyout not occur... Well, at least not yet.

So, yes, as ISIS shares near an inflection point (in fact, two distinct inflection points from opposite directions), a big move appears imminent. Multiple levels of trading support lie at ~$10, and multiple levels of resistance converge at ~$11.50. This translates as an approximately 10% range between the two. This squeeze can continue to compress, could even breakdown albeit ephemerally; upside momentum, however, busily and quickly refreshes itself. And nears completion. The moment -- a breakout in one direction or the other -- appears nigh. I believe the breakout will be up. (btw, please recall that investor support lies at ~$8, above which the long term dynamics for this stock changed immediately and positively. The difference is time frame, and thus objectives. Always align the two!)

Thus, I place this opportunity front & center. It joins other recent winners, which includes among other favorites, Apple Computer/AAPL (remember that one, naysayers?) and Zumiez/ZUMZ -- which also nears an explosive move higher.
-- David M Gordon / The Deipnosophist